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Document type:
Proceedings Paper
Author(s):
Rossmann, E; Kitiratschky, V; Hofmann, H; Simon, MM; Kraiczy, P; Wallich, R
Title:
BbCRASP-1 of the Lyme disease spirochetes induces antibodies to non-denatured structural determinants in humans
Abstract:
BbCRASP-1 is the dominant factor H and FHL-1 binding protein of Lyme disease spirochetes and is suggested to contribute to the persistence of the pathogen in mammals. Here, we show that serum samples from patients with Lyme disease contain antibodies generated to BbCRASP-1 that are exclusively directed to non-denatured structural determinants but not to denatured protein. (C) 2008 Elsevier GrnbH. All rights reserved.
Journal title abbreviation:
Int J Med Microbiol
Year:
2008
Journal volume:
298 Suppl.
Pages contribution:
284-286
Language:
eng
Print-ISSN:
1438-4221
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie
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