Radiochemical F-18-fluoroarylation of unsaturated alpha-, beta- and gamma-amino acids, application to a radiolabelled analogue of baclofen

Titel:: Radiochemical F-18-fluoroarylation of unsaturated alpha-, beta- and gamma-amino acids, application to a radiolabelled analogue of baclofen
Dokumenttyp:: Article
Autor(en):: Höfling, SB; Hultsch, C; Wester, HJ; Heinrich, MR
Abstract:: Unsaturated alpha-, beta- and gamma-amino acids have been investigated as substrates for the reductive Meerwein arylation. Radical reactions of this type have been shown to be a valuable tool for the fast and efficient introduction of the 4-[F-18]fluorophenyl group into precursor molecules allowing short-time syntheses of potential PET radiotracers, which would be more difficult to access by other methods. (C) 2008 Elsevier Ltd. All rights reserved.
Zeitschriftentitel:: Tetrahedron
Jahr:: 2008
Band / Volume:: 64
Heft / Issue:: 52
Seitenangaben Beitrag:: 11846-11851
Sprache:: eng
Print-ISSN:: 0040-4020
TUM Einrichtung:: Klinik und Poliklinik für Nuklearmedizin
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