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Title:

Long-term immunity against actual poxviral HLA ligands as identified by differential stable isotope labeling.

Document type:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Meyer, VS; Kastenmuller, W; Gasteiger, G; Franz-Wachtel, M; Lamkemeyer, T; Rammensee, HG; Stevanovic, S; Sigurdardottir, D; Drexler, I
Abstract:
Viral peptides are presented by HLA class I on infected cells to activate CD8(+) T cells. Several immunogenic peptides have been identified indirectly by epitope prediction and screening of T cell responses to poxviral vectors, including modified vaccinia virus Ankara (MVA) currently being tested as recombinant or smallpox vaccines. However, for the development of optimal vaccination and immunomonitoring strategies, it is essential to characterize the actual viral HLA ligand repertoire of infect...     »
Journal title abbreviation:
J Immunol
Year:
2008
Journal volume:
181
Journal issue:
9
Pages contribution:
6371-83
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18941228
Print-ISSN:
0022-1767
TUM Institution:
Institut für Virologie
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