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Title:

Cardiovascular Effects of the n-Butanol Extract from Kalanchoe Crenata Leaves

Document type:
Article
Author(s):
Nguelefack, TB; Dimo, T; Dongmo, AB; Sontia, B; Fotio, AL; Watcho, P; Kamanyi, A; Vierling, W
Abstract:
The present work examined the effects of the n-butanol extract from the leaves of Kalanchoe crenata (Andrews) Haworth (Crassulaceae) on rat blood pressure and guinea pig papillary muscle contraction and action potential. When administered intravenously at doses of 2, 5, and 10 mg/kg, the n-butanol extract of K. crenata leaves induced a significant transient fall in blood pressure and significantly reduced the cardiac rate for about 10 min. Concomitantly, the extract significantly increased the P...     »
Journal title abbreviation:
Pharm Biol
Year:
2008
Journal volume:
46
Journal issue:
12
Pages contribution:
846-853
Language:
eng
Print-ISSN:
0553-9323
TUM Institution:
Institut für Pharmakologie und Toxikologie
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