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Titel:

Signaling through cGMP-dependent protein kinase I in the amygdala is critical for auditory-cued fear memory and long-term potentiation.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Paul, C; Schoberl, F; Weinmeister, P; Micale, V; Wotjak, CT; Hofmann, F; Kleppisch, T
Abstract:
Long-term potentiation (LTP) of inputs relaying sensory information from cortical and thalamic neurons to principal neurons in the lateral amygdala (LA) is thought to serve as a cellular mechanism for associative fear learning. Nitric oxide (NO), a messenger molecule widely implicated in synaptic plasticity and behavior, has been shown to enhance LTP in the LA as well as consolidation of associative fear memory. Additional evidence suggests that NO-induced enhancement of LTP and amygdala-depende...     »
Zeitschriftentitel:
J Neurosci
Jahr:
2008
Band / Volume:
28
Heft / Issue:
52
Seitenangaben Beitrag:
14202-12
Sprache:
eng
Volltext / DOI:
doi:10.1523/JNEUROSCI.2216-08.2008
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19109502
Print-ISSN:
0270-6474
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie
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