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Title:

Differential capacity of chaperone-rich lysates in cross-presenting human endogenous and exogenous melanoma differentiation antigens.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Bleifuss, E; Bendz, H; Sirch, B; Thompson, S; Brandl, A; Milani, V; Graner, MW; Drexler, I; Kuppner, M; Katsanis, E; Noessner, E; Issels, RD
Abstract:
The goal of immune-based tumor therapies is the activation of immune cells reactive against a broad spectrum of tumor-expressed antigens. Vaccines based on chaperone proteins appear promising as these proteins naturally exist as complexes with various protein fragments including those derived from tumor-associated antigens. Multi-chaperone systems are expected to have highest polyvalency as different chaperones can carry distinct sets of antigenic fragments. A free-solution isoelectric focusing...     »
Journal title abbreviation:
Int J Hyperthermia
Year:
2008
Journal volume:
24
Journal issue:
8
Pages contribution:
623-37
Language:
eng
Fulltext / DOI:
doi:10.1080/02656730802213384
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18608582
Print-ISSN:
0265-6736
TUM Institution:
Institut für Virologie
 BibTeX