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Document type:
Journal Article; Article 
Author(s):
Riemenschneider, M; Schoepfer-Wendels, A; Friedrich, P; Konta, L; Laws, SM; Mueller, JC; Kurz, A; Förstl, H 
Title:
No association of vacuolar protein sorting 26 polymorphisms with Alzheimer's disease. 
Abstract:
Using a case-control sample we evaluated a possible involvement of the Vacuolar protein sorting 26 (VPS26) gene in the pathogenesis of AD. VPS26 located at 10q22.1 denotes a retromer subunit functionally involved in the cellular trafficking of Memapsin 2 (BACE). Genotyping of eight single nucleotide polymorphisms covering the complete VPS26 gene and haplotypic analysis revealed no association with AD. Thus, we conclude that VPS26 can be excluded as a major positional and functional candidate gen...    »
 
Journal title abbreviation:
Neurobiol Aging 
Year:
2007 
Journal volume:
28 
Journal issue:
Pages contribution:
883-4 
Language:
eng 
Print-ISSN:
0197-4580 
TUM Institution:
Klinik und Poliklinik für Psychiatrie und Psychotherapie