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Titel:

Premature apoptosis of Chlamydia-infected cells disrupts chlamydial development.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Ying, S; Pettengill, M; Latham, ER; Walch, A; Ojcius, DM; Häcker, G
Abstract:
The obligate intracellular development of Chlamydia suggests that the bacteria should be vulnerable to premature host cell apoptosis, but because Chlamydia-infected cells are apoptosis resistant, this has never been able to be tested. We have devised a system to circumvent the apoptotic block imposed by chlamydial infection. When the proapoptotic protein Bim(S) was experimentally induced, epithelial cells underwent apoptosis that was not blocked by chlamydial infection. Apoptosis during the deve...     »
Zeitschriftentitel:
J Infect Dis
Jahr:
2008
Band / Volume:
198
Heft / Issue:
10
Seitenangaben Beitrag:
1536-44
Sprache:
eng
Volltext / DOI:
doi:10.1086/592755
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18821848
Print-ISSN:
0022-1899
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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