User: Guest  Login
More Searchfields
Simple search
Title:

Premature apoptosis of Chlamydia-infected cells disrupts chlamydial development.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Ying, S; Pettengill, M; Latham, ER; Walch, A; Ojcius, DM; Häcker, G
Abstract:
The obligate intracellular development of Chlamydia suggests that the bacteria should be vulnerable to premature host cell apoptosis, but because Chlamydia-infected cells are apoptosis resistant, this has never been able to be tested. We have devised a system to circumvent the apoptotic block imposed by chlamydial infection. When the proapoptotic protein Bim(S) was experimentally induced, epithelial cells underwent apoptosis that was not blocked by chlamydial infection. Apoptosis during the deve...     »
Journal title abbreviation:
J Infect Dis
Year:
2008
Journal volume:
198
Journal issue:
10
Pages contribution:
1536-44
Language:
eng
Fulltext / DOI:
doi:10.1086/592755
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18821848
Print-ISSN:
0022-1899
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
 BibTeX