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Titel:

Cationic liposomes formulated with synthetic mycobacterial cordfactor (CAF01): a versatile adjuvant for vaccines with different immunological requirements.

Dokumenttyp:
Journal Article
Autor(en):
Agger, EM; Rosenkrands, I; Hansen, J; Brahimi, K; Vandahl, BS; Aagaard, C; Werninghaus, K; Kirschning, C; Lang, R; Christensen, D; Theisen, M; Follmann, F; Andersen, P
Abstract:
BACKGROUND: It is now emerging that for vaccines against a range of diseases including influenza, malaria and HIV, the induction of a humoral response is insufficient and a substantial complementary cell-mediated immune response is necessary for adequate protection. Furthermore, for some diseases such as tuberculosis, a cellular response seems to be the sole effector mechanism required for protection. The development of new adjuvants capable of inducing highly complex immune responses with stron...     »
Zeitschriftentitel:
PLoS ONE
Jahr:
2008
Band / Volume:
3
Heft / Issue:
9
Seitenangaben Beitrag:
e3116
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.pone.0003116
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18776936
Print-ISSN:
1932-6203
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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