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Title:

Expression pattern analysis of transcribed HERV sequences is complicated by ex vivo recombination.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Flockerzi, A; Maydt, J; Frank, O; Ruggieri, A; Maldener, E; Seifarth, W; Medstrand, P; Lengauer, T; Meyerhans, A; Leib-Mösch, C; Meese, E; Mayer, J
Abstract:
BACKGROUND: The human genome comprises numerous human endogenous retroviruses (HERVs) that formed millions of years ago in ancestral species. A number of loci of the HERV-K(HML-2) family are evolutionarily much younger. A recent study suggested an infectious HERV-K(HML-2) variant in humans and other primates. Isolating such a variant from human individuals would be a significant finding for human biology. RESULTS: When investigating expression patterns of specific HML-2 proviruses we encountered...     »
Journal title abbreviation:
Retrovirology
Year:
2007
Journal volume:
4
Pages contribution:
39
Language:
eng
Fulltext / DOI:
doi:10.1186/1742-4690-4-39
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/17550625
TUM Institution:
Institut für Virologie
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