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Titel:

Long-term HIV-1 infection of neural progenitor populations.

Dokumenttyp:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Rothenaigner, I; Kramer, S; Ziegler, M; Wolff, H; Kleinschmidt, A; Brack-Werner, R
Abstract:
BACKGROUND: HIV can reside in the brain for many years. While astrocytes are known to tolerate long-term HIV infection, the potential of other neural cell types to harbour HIV is unclear. OBJECTIVE: To investigate whether HIV can persist in neural progenitor cell populations. DESIGN: A multipotent human neural stem cell line (HNSC.100) was used to compare HIV infection in neural progenitor and astrocyte cell populations. METHODS: Expression of cellular genes/proteins was analysed by real-time re...     »
Zeitschriftentitel:
AIDS
Jahr:
2007
Band / Volume:
21
Heft / Issue:
17
Seitenangaben Beitrag:
2271-81
Sprache:
eng
Volltext / DOI:
doi:10.1097/QAD.0b013e3282f12f27
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18090275
Print-ISSN:
0269-9370
TUM Einrichtung:
Institut für Virologie
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