User: Guest  Login
Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Frank, B; Bermejo, JL; Hemminki, K; Sutter, C; Wappenschmidt, B; Meindl, A; Kiechle-Bahat, M; Bugert, P; Schmutzler, RK; Bartram, CR; Burwinkel, B
Title:
Copy number variant in the candidate tumor suppressor gene MTUS1 and familial breast cancer risk.
Abstract:
Copy number variants (CNVs), insertions, deletions and duplications, contribute considerably to human genetic variation and disease development. A recent study has characterized 100 CNVs including a deletion in the mitochondrial tumor suppressor gene 1 (MTUS1) lacking the coding exon 4. MTUS1 maps to chromosome 8p, a region frequently deleted and associated with disease progression in human cancers, including breast cancer (BC). To investigate the effect of the MTUS1 CNV on familial BC risk, we...    »
Journal title abbreviation:
Carcinogenesis
Year:
2007
Journal volume:
28
Journal issue:
7
Pages contribution:
1442-5
Language:
eng
Fulltext / DOI:
doi:10.1093/carcin/bgm033
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/17301065
Print-ISSN:
0143-3334
TUM Institution:
Frauenklinik und Poliklinik
 BibTeX