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Title:

Comparison of gene expression data from human and mouse breast cancers: identification of a conserved breast tumor gene set.

Document type:
Comparative Study; Journal Article; Article
Author(s):
Klein, A; Wessel, R; Graessmann, M; Jürgens, M; Petersen, I; Schmutzler, R; Niederacher, D; Arnold, N; Meindl, A; Scherneck, S; Seitz, S; Graessmann, A
Abstract:
The aim of our work was to establish a database for breast cancer gene expression data in order to compare human and mouse breast cancer. We identified human and mouse homologues genes and compared the expression profile of 24 human breast tumors with 6 WAP-SVT/t breast tumors (WAP-SVT/t animals, line 8). Our studies confirmed the heterogeneity in gene expression of human as well as mouse breast cancer cells. However, 63 genes were found to be differentially expressed (upregulated: 40; downregu...     »
Journal title abbreviation:
Int J Cancer
Year:
2007
Journal volume:
121
Journal issue:
3
Pages contribution:
683-8
Language:
eng
Fulltext / DOI:
doi:10.1002/ijc.22630
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/17410534
Print-ISSN:
0020-7136
TUM Institution:
Frauenklinik und Poliklinik
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