User: Guest  Login
Document type:
Journal Article; Article 
Author(s):
Wagner, U; du Bois, A; Pfisterer, J; Huober, J; Loibl, S; Luck, HJ; Sehouli, J; Gropp, M; Stahle, A; Schmalfeldt, B; Meier, W; Jackisch, C 
Title:
Gefitinib in combination with tamoxifen in patients with ovarian cancer refractory or resistant to platinum-taxane based therapy--a phase II trial of the AGO Ovarian Cancer Study Group (AGO-OVAR 2.6). 
Abstract:
BACKGROUND: Tamoxifen and gefitinib (IRESSA) combination therapy was studied in patients with ovarian cancer refractory or resistant to platinum- and taxane-based therapy. PATIENTS AND METHODS: In this phase II study, 56 patients with epithelial ovarian carcinoma or cancer of the fallopian tube or peritoneum received oral tamoxifen 40 mg/day and gefitinib 500 mg/day until progression or unacceptable toxicity. RESULTS: Seventeen patients (mean age: 59.6 years) had previously received first-line p...    »
 
Journal title abbreviation:
Gynecol Oncol 
Year:
2007 
Journal volume:
105 
Journal issue:
Pages contribution:
132-7 
Language:
eng 
Print-ISSN:
0090-8258 
TUM Institution:
Frauenklinik und Poliklinik