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Title:

A genome-wide analysis of LPS tolerance in macrophages.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Mages, J; Dietrich, H; Lang, R
Abstract:
Among the multiple mechanisms that control the intensity and duration of macrophage activation, the development of a state of refractoriness to a second stimulation in cells treated with lipopolysaccharide (LPS) has long been recognized. Release of inhibitory cytokines and alterations in intracellular signaling pathways may be involved in the development of LPS tolerance. Although a number of molecules have been implicated, a detailed picture of the molecular changes in LPS tolerance is still mi...     »
Journal title abbreviation:
Immunobiology
Year:
2007
Journal volume:
212
Journal issue:
9-10
Pages contribution:
723-37
Language:
eng
Fulltext / DOI:
doi:10.1016/j.imbio.2007.09.015
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18086374
Print-ISSN:
0171-2985
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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