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Titel:

BAC to immunology--bacterial artificial chromosome-mediated transgenesis for targeting of immune cells.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Review
Autor(en):
Sparwasser, T; Eberl, G
Abstract:
Thirty years after the first transgenic mouse was produced, a plethora of genetic tools has been developed to study immune cells in vivo. A powerful development is the bacterial artificial chromosome (BAC) transgenic approach, combining advantages of both conventional transgenic and knock-in gene-targeting strategies. In immunology the potential of BAC transgenic technology has yet to be fully harvested and, combined with a variety of elegant genetic tools, it will allow the analysis of complex...     »
Zeitschriftentitel:
Immunology
Jahr:
2007
Band / Volume:
121
Heft / Issue:
3
Seitenangaben Beitrag:
308-13
Sprache:
eng
Volltext / DOI:
doi:10.1111/j.1365-2567.2007.02605.x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/17437533
Print-ISSN:
0019-2805
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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