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Titel:

Carcinogenic hypergastrinemia: signet-ring cell carcinoma in a patient with multiple endocrine neoplasia type 1 with Zollinger-Ellison's syndrome.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Schott, M; Sagert, C; Willenberg, HS; Schinner, S; Ramp, U; Varro, A; Raffel, A; Eisenberger, C; Zacharowski, K; Perren, A; Scherbaum, WA
Abstract:
CONTEXT: Gastric neuroendocrine tumors are rare neoplasms that originate from gastric enterochromaffin-like (ECL) cells in the oxyntic mucosa. Gastrin and its derivates have been reported to regulate epithelial cell proliferation, migration, and differentiation. Mutations in the epithelial cadherin (E-cadherin) gene have been shown to be associated with the occurrence of diffuse gastric carcinomas in affected families. OBJECTIVE: In this study we investigated the histopathological and molecular...     »
Zeitschriftentitel:
J Clin Endocrinol Metab
Jahr:
2007
Band / Volume:
92
Heft / Issue:
9
Seitenangaben Beitrag:
3378-82
Sprache:
eng
Volltext / DOI:
doi:10.1210/jc.2007-0283
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/17609302
Print-ISSN:
0021-972X
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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