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Title:

WHO 2004 Criteria and CK19 are Reliable Prognostic Markers in Pancreatic Endocrine Tumors.

Document type:
Journal Article
Author(s):
Schmitt, AM; Anlauf, M; Rousson, V; Schmid, S; Kofler, A; Riniker, F; Bauersfeld, J; Barghorn, A; Probst-Hensch, NM; Moch, H; Heitz, PU; Kloeppel, G; Komminoth, P; Perren, A
Abstract:
BACKGROUND: It is difficult to predict the biologic behavior of pancreatic endocrine tumors in absence of metastases or invasion into adjacent organs. The World Health Organization (WHO) has proposed in 2004 size, angioinvasion, mitotic activity, and MIB1 proliferation index as prognostic criteria. Our aim was to test retrospectively the predictive value of these 2004 WHO criteria and of CK19, CD99, COX2, and p27 immunohistochemistry in a large series of patients with long-term follow-up. DESIGN...     »
Journal title abbreviation:
Am J Surg Pathol
Year:
2007
Journal volume:
31
Journal issue:
11
Pages contribution:
1677-1682
Language:
eng
Fulltext / DOI:
doi:10.1097/PAS.0b013e31805f675d
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18059224
Print-ISSN:
0147-5185
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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