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Title:

[Gastrin cell hyperplasia associated with duodenal MEN1-related gastrinomas: histopathology and genetics]

Document type:
English Abstract; Journal Article
Author(s):
Anlauf, M; Perren, A; Klöppel, G
Abstract:
AIMS: The identification of precursor lesions has a great impact on our understanding of tumorigenesis. In this study we investigated whether preneoplastic lesions can be identified in sporadic gastrinomas and in gastrinomas in multiple endocrine neoplasia type 1 (MEN1) patients. These lesions were tested for loss of heterozygosity (LOH) of the MEN1 gene locus on chromosome 11q13. MATERIAL AND METHODS: Tissue specimens from 25 patients with Zollinger-Ellison syndrome (ZES) were analyzed. The MEN...     »
Journal title abbreviation:
Verh Dtsch Ges Pathol
Year:
2007
Journal volume:
91
Pages contribution:
320-9
Language:
de
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18314630
Print-ISSN:
0070-4113
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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