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Title:

The E-cadherin Repressor Snail Plays a Role in Tumor Progression of Endometrioid Adenocarcinomas.

Document type:
Journal Article
Author(s):
Blechschmidt, K; Kremmer, E; Hollweck, R; Mylonas, I; Höfler, H; Kremer, M; Becker, KF
Abstract:
Endometrial cancer is the most common gynecologic cancer in the developed world. The cell-adhesion protein E-cadherin acts as a tumor-suppressor protein and is down-regulated by the transcription factor Snail, whose expression was shown to be associated with estrogen receptor signaling. This study aimed to investigate the expression of E-cadherin, Snail, and estrogen-receptor alpha in 87 primary tumors and 26 metastases of endometroid endometrial carcinomas. Reduced E-cadherin immunoreactivity w...     »
Journal title abbreviation:
Diagn Mol Pathol
Year:
2007
Journal volume:
16
Journal issue:
4
Pages contribution:
222-228
Language:
eng
Fulltext / DOI:
doi:10.1097/PDM.0b013e31806219ae
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18043286
Print-ISSN:
1052-9551
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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