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Titel:

The E-cadherin Repressor Snail Plays a Role in Tumor Progression of Endometrioid Adenocarcinomas.

Dokumenttyp:
Journal Article
Autor(en):
Blechschmidt, K; Kremmer, E; Hollweck, R; Mylonas, I; Höfler, H; Kremer, M; Becker, KF
Abstract:
Endometrial cancer is the most common gynecologic cancer in the developed world. The cell-adhesion protein E-cadherin acts as a tumor-suppressor protein and is down-regulated by the transcription factor Snail, whose expression was shown to be associated with estrogen receptor signaling. This study aimed to investigate the expression of E-cadherin, Snail, and estrogen-receptor alpha in 87 primary tumors and 26 metastases of endometroid endometrial carcinomas. Reduced E-cadherin immunoreactivity w...     »
Zeitschriftentitel:
Diagn Mol Pathol
Jahr:
2007
Band / Volume:
16
Heft / Issue:
4
Seitenangaben Beitrag:
222-228
Sprache:
eng
Volltext / DOI:
doi:10.1097/PDM.0b013e31806219ae
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18043286
Print-ISSN:
1052-9551
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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