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Titel:

Fetomaternal immune cross talk modifies T-cell priming through sustained changes to DC function.

Dokumenttyp:
Article; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Lacorcia, Matthew; Bhattacharjee, Sonakshi; Laubhahn, Kristina; Alhamdan, Fahd; Ram, Marija; Muschaweckh, Andreas; Potaczek, Daniel P; Kosinska, Anna; Garn, Holger; Protzer, Ulrike; Renz, Harald; Prazeres da Costa, Clarissa
Abstract:
BACKGROUND: Prenatal exposure to infections can modify immune development. These environmental disturbances during early life potentially alter the incidence of inflammatory disorders as well as priming of immune responses. Infection with the helminth Schistosoma mansoni is widely studied for its ability to alter immune responsiveness and is associated with variations in coinfection, allergy, and vaccine efficacy in endemic populations. OBJECTIVE: Exposure to maternal schistosomiasis during earl...     »
Zeitschriftentitel:
J Allergy Clin Immunol
Jahr:
2021
Band / Volume:
148
Heft / Issue:
3
Seitenangaben Beitrag:
843-857.e6
Volltext / DOI:
doi:10.1016/j.jaci.2021.02.031
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33684437
Print-ISSN:
0091-6749
TUM Einrichtung:
611; Institut für Medizinische Mikrobiologie, Immunologie und Hygiene; Institut für Virologie
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