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- Title:
Multicentre comparison of quantitative PCR-based assays to detect SARS-CoV-2, Germany, March 2020.
- Document type:
- Article; Comparative Study; Journal Article; Multicenter Study
- Author(s):
- Muenchhoff, Maximilian; Mairhofer, Helga; Nitschko, Hans; Grzimek-Koschewa, Natascha; Hoffmann, Dieter; Berger, Annemarie; Rabenau, Holger; Widera, Marek; Ackermann, Nikolaus; Konrad, Regina; Zange, Sabine; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Sing, Andreas; Liebl, Bernhard; Wölfel, Roman; Ciesek, Sandra; Drosten, Christian; Protzer, Ulrike; Boehm, Stephan; Keppler, Oliver T
- Abstract:
- Containment strategies and clinical management of coronavirus disease (COVID-19) patients during the current pandemic depend on reliable diagnostic PCR assays for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we compare 11 different RT-PCR test systems used in seven diagnostic laboratories in Germany in March 2020. While most assays performed well, we identified detection problems in a commonly used assay that may have resulted in false-negative test results during the... »
- Journal title abbreviation:
- Euro Surveill
- Year:
- 2020
- Journal volume:
- 25
- Journal issue:
- 24
- Pages contribution:
- 2-6
- Fulltext / DOI:
- doi:10.2807/1560-7917.ES.2020.25.24.2001057
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/32583765
- Print-ISSN:
- 1025-496X
- TUM Institution:
- Institut für Virologie
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