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Titel:

Efficient and reproducible depletion of hepatitis B virus from plasma derived extracellular vesicles.

Dokumenttyp:
Journal Article
Autor(en):
Jung, Stephanie; Jacobs, Karolin Fiona Kirsten; Shein, Mikhail; Schütz, Anne Kathrin; Mohr, Fabian; Stadler, Herbert; Stadler, Daniela; Lucko, Aaron Michael; Altstetter, Sebastian Maximilian; Wilsch, Florian; Deng, Li; Protzer, Ulrike
Abstract:
Extracellular vesicles (EVs) are emerging fundamental players in viral infections by shuttling viral components, mediating immune responses and likely the spread of the virus. However, the obstacles involved in purifying EVs and removing contaminating viral particles in a reliable and effective manner bottlenecks the full potential for the development of clinical and diagnostic treatment options targeting EV. Because of the similarities in size, density, membrane composition and mode of biogenes...     »
Zeitschriftentitel:
J Extracell Vesicles
Jahr:
2020
Band / Volume:
10
Heft / Issue:
2
Volltext / DOI:
doi:10.1002/jev2.12040
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33363711
TUM Einrichtung:
Institut für Virologie
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