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Titel:

MbnC Is Not Required for the Formation of the N-Terminal Oxazolone in the Methanobactin from Methylosinus trichosporium OB3b.

Dokumenttyp:
Journal Article
Autor(en):
Dershwitz, Philip; Gu, Wenyu; Roche, Julien; Kang-Yun, Christina S; Semrau, Jeremy D; Bobik, Thomas A; Fulton, Bruce; Zischka, Hans; DiSpirito, Alan A
Abstract:
Methanobactins (MBs) are ribosomally synthesized and posttranslationally modified peptides (RiPPs) produced by methanotrophs for copper uptake. The posttranslational modification that defines MBs is the formation of two heterocyclic groups with associated thioamines from X-Cys dipeptide sequences. Both heterocyclic groups in the MB from Methylosinus trichosporium OB3b (MB-OB3b) are oxazolone groups. The precursor gene for MB-OB3b is mbnA, which is part of a gene cluster that contains both annota...     »
Zeitschriftentitel:
Appl Environ Microbiol
Jahr:
2022
Band / Volume:
88
Heft / Issue:
2
Volltext / DOI:
doi:10.1128/AEM.01841-21
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/34731053
Print-ISSN:
0099-2240
TUM Einrichtung:
Institut für Toxikologie und Umwelthygiene
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