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Titel:

Mitochondria in non-alcoholic fatty liver disease.

Dokumenttyp:
Journal Article
Autor(en):
Simões, Inês C M; Fontes, Adriana; Pinton, Paolo; Zischka, Hans; Wieckowski, Mariusz R
Abstract:
NAFLD is a common disease in Western society and ranges from steatosis to steatohepatitis and to end-stage liver disease. The molecular mechanisms that cause the progression of steatosis to severe liver damage are not fully understood. One suggested mechanism involves the oxidation of biomolecules by mitochondrial ROS which initiates a vicious cycle of exacerbated mitochondrial dysfunction and increased hepatocellular oxidative damage. This may ultimately pave the way for hepatic inflammation an...     »
Zeitschriftentitel:
Int J Biochem Cell Biol
Jahr:
2018
Band / Volume:
95
Seitenangaben Beitrag:
93-99
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.biocel.2017.12.019
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29288054
Print-ISSN:
1357-2725
TUM Einrichtung:
Institut für Toxikologie und Umwelthygiene
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