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Title:

The cGMP system: components and function.

Document type:
Journal Article; Review
Author(s):
Hofmann, Franz
Abstract:
The cyclic guanosine monophosphate (cGMP) signaling system is one of the most prominent regulators of a variety of physiological and pathophysiological processes in many mammalian and non-mammalian tissues. Targeting this pathway by increasing cGMP levels has been a very successful approach in pharmacology as shown for nitrates, phosphodiesterase (PDE) inhibitors and stimulators of nitric oxide-guanylyl cyclase (NO-GC) and particulate GC (pGC). This is an introductory review to the cGMP signalin...     »
Journal title abbreviation:
Biol Chem
Year:
2020
Journal volume:
401
Journal issue:
4
Pages contribution:
447-469
Fulltext / DOI:
doi:10.1515/hsz-2019-0386
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/31747372
Print-ISSN:
1431-6730
TUM Institution:
Institut für Pharmakologie und Toxikologie
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