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Title:

Non-coding RNAs: update on mechanisms and therapeutic targets from the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart.

Document type:
Article; Proceedings Paper; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Bär, Christian; Chatterjee, Shambhabi; Falcão Pires, Inês; Rodrigues, Patrícia; Sluijter, Joost P G; Boon, Reinier A; Nevado, Rosa M; Andrés, Vicente; Sansonetti, Marida; de Windt, Leon; Ciccarelli, Michele; Hamdani, Nazha; Heymans, Stephane; Figuinha Videira, Raquel; Tocchetti, Carlo G; Giacca, Mauro; Zacchigna, Serena; Engelhardt, Stefan; Dimmeler, Stefanie; Madonna, Rosalinda; Thum, Thomas
Abstract:
Vast parts of mammalian genomes are actively transcribed, predominantly giving rise to non-coding RNA (ncRNA) transcripts including microRNAs, long ncRNAs, and circular RNAs among others. Contrary to previous opinions that most of these RNAs are non-functional molecules, they are now recognized as critical regulators of many physiological and pathological processes including those of the cardiovascular system. The discovery of functional ncRNAs has opened up new research avenues aiming at unders...     »
Journal title abbreviation:
Cardiovasc Res
Year:
2020
Journal volume:
116
Journal issue:
11
Pages contribution:
1805-1819
Fulltext / DOI:
doi:10.1093/cvr/cvaa195
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/32638021
Print-ISSN:
0008-6363
TUM Institution:
Institut für Pharmakologie und Toxikologie
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