Emerging Alternative Functions for the Auxiliary Subunits of the Voltage-Gated Calcium Channels.

Titel:: Emerging Alternative Functions for the Auxiliary Subunits of the Voltage-Gated Calcium Channels.
Dokumenttyp:: Journal Article; Research Support, Non-U.S. Gov't; Review; Article
Autor(en):: Hofmann, Franz; Belkacemi, Anouar; Flockerzi, Veit
Abstract:: Voltage gated calcium channels (Cav) are composed of up to five proteins: The ion conducting pore subunit ?1 and the auxiliary subunits ?2, ?, ?, and ?. Recent reports show that Cav?1 and Cav? comprise the calcium channel core complex and that ?, ?2 ? and ? may serve additional roles that are independent of the Cav?1 subunit. This short review will summarize these emerging functions.
Zeitschriftentitel:: Curr Mol Pharmacol
Jahr:: 2015
Band / Volume:: 8
Heft / Issue:: 2
Seitenangaben Beitrag:: 162-8
Sprache:: eng
PubMed:: http://view.ncbi.nlm.nih.gov/pubmed/25966689
Print-ISSN:: 1874-4672
TUM Einrichtung:: Institut für Pharmakologie und Toxikologie
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