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Titel:

Analysis of calcium channels by conditional mutagenesis.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Review
Autor(en):
Moosmang, S; Kleppisch, T; Wegener, J; Welling, A; Hofmann, F
Abstract:
Ca2+ influx through various ion channels is an important determinant of the cytosolic Ca2+ concentration, which plays a pivotal role in countless cellular processes. The cardiac L-type Ca2+ channel, Ca(v)1.2, represents a major pathway for Ca2+ entry and is in many cells expressed together with other high- and low-voltage-activated Ca2+ channels. This article will focus on the use of conditional transgenic mouse models to clarify the roles of Ca2+ channels in several biological systems. The phen...     »
Zeitschriftentitel:
Handb Exp Pharmacol
Jahr:
2007
Band / Volume:
178
Seitenangaben Beitrag:
469-90
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/17203667
Print-ISSN:
0171-2004
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie
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