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Titel:

H19 Induces Abdominal Aortic Aneurysm Development and Progression.

Dokumenttyp:
Article; Journal Article
Autor(en):
Li, Daniel Y; Busch, Albert; Jin, Hong; Chernogubova, Ekaterina; Pelisek, Jaroslav; Karlsson, Joakim; Sennblad, Bengt; Liu, Shengliang; Lao, Shen; Hofmann, Patrick; Bäcklund, Alexandra; Eken, Suzanne M; Roy, Joy; Eriksson, Per; Dacken, Brian; Ramanujam, Deepak; Dueck, Anne; Engelhardt, Stefan; Boon, Reinier A; Eckstein, Hans-Henning; Spin, Joshua M; Tsao, Philip S; Maegdefessel, Lars
Abstract:
BACKGROUND: Long noncoding RNAs have emerged as critical molecular regulators in various biological processes and diseases. Here we sought to identify and functionally characterize long noncoding RNAs as potential mediators in abdominal aortic aneurysm development. METHODS: We profiled RNA transcript expression in 2 murine abdominal aortic aneurysm models, Angiotensin II (ANGII) infusion in apolipoprotein E-deficient ( ApoE-/-) mice (n=8) and porcine pancreatic elastase instillation in C57BL/6 w...     »
Zeitschriftentitel:
Circulation
Jahr:
2018
Band / Volume:
138
Heft / Issue:
15
Seitenangaben Beitrag:
1551-1568
Volltext / DOI:
doi:10.1161/CIRCULATIONAHA.117.032184
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29669788
Print-ISSN:
0009-7322
TUM Einrichtung:
Fachgebiet Gefäßchirurgie (Prof. Eckstein); Institut für Pharmakologie und Toxikologie
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