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Titel:

Intraperitoneal Oil Application Causes Local Inflammation with Depletion of Resident Peritoneal Macrophages.

Dokumenttyp:
Journal Article
Autor(en):
Alsina-Sanchis, Elisenda; Mülfarth, Ronja; Moll, Iris; Mogler, Carolin; Rodriguez-Vita, Juan; Fischer, Andreas
Abstract:
Oil is frequently used as a solvent to inject lipophilic substances into the peritoneum of laboratory animals. Although mineral oil causes chronic peritoneal inflammation, little is known whether other oils are better suited. We show that olive, peanut, corn, or mineral oil causes xanthogranulomatous inflammation with depletion of resident peritoneal macrophages. However, there were striking differences in the severity of the inflammatory response. Peanut and mineral oil caused severe chronic in...     »
Zeitschriftentitel:
Mol Cancer Res
Jahr:
2021
Band / Volume:
19
Heft / Issue:
2
Seitenangaben Beitrag:
288-300
Volltext / DOI:
doi:10.1158/1541-7786.MCR-20-0650
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33139505
Print-ISSN:
1541-7786
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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