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Titel:

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.

Dokumenttyp:
journal article
Autor(en):
Ricketts, Christopher J; De Cubas, Aguirre A; Fan, Huihui; Smith, Christof C; Lang, Martin; Reznik, Ed; Bowlby, Reanne; Gibb, Ewan A; Akbani, Rehan; Beroukhim, Rameen; Bottaro, Donald P; Choueiri, Toni K; Gibbs, Richard A; Godwin, Andrew K; Haake, Scott; Hakimi, A Ari; Henske, Elizabeth P; Hsieh, James J; Ho, Thai H; Kanchi, Rupa S; Krishnan, Bhavani; Kwaitkowski, David J; Lui, Wembin; Merino, Maria J; Mills, Gordon B; Myers, Jerome; Nickerson, Michael L; Reuter, Victor E; Schmidt, Laura S; Shel...     »
Abstract:
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with different genetic drivers, clinical courses, and therapeutic responses. The current study evaluated 843 RCC from the three major histologic subtypes, including 488 clear cell RCC, 274 papillary RCC, and 81 chromophobe RCC. Comprehensive genomic and phenotypic analysis of the RCC subtypes reveals distinctive features of each subtype that provide the foundation for the development of subtype-specifi...     »
Zeitschriftentitel:
Cell Rep
Jahr:
2018
Band / Volume:
23
Heft / Issue:
1
Seitenangaben Beitrag:
313-326.e5
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.celrep.2018.03.075
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29617669
TUM Einrichtung:
Institut für Allgemeine Pathologie und pathologische Anatomie
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