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Title:

An Open-Labeled Study on Fecal Microbiota Transfer in Irritable Bowel Syndrome Patients Reveals Improvement in Abdominal Pain Associated with the Relative Abundance of Akkermansia Muciniphila.

Document type:
Journal Article
Author(s):
Cruz-Aguliar, Rebeca M; Wantia, Nina; Clavel, Thomas; Vehreschild, Maria J G T; Buch, Thorsten; Bajbouj, Monther; Haller, Dirk; Busch, Dirk; Schmid, Roland M; Stein-Thoeringer, Christoph K
Abstract:
BACKGROUND/AIMS: The gut microbiota is altered in irritable bowel syndrome (IBS), and microbiota manipulations by diet or antibiotics can reduce its symptoms. As fecal microbiota transfer (FMT) in IBS is still controversial, we investigated the clinical and side effects of FMT in a cohort of IBS patients with recurrent, treatment refractory symptoms, and studied gut microbiota signatures. METHODS: Using an observational, prospective study design, we applied FMTs from one unrelated, healthy donor...     »
Journal title abbreviation:
Digestion
Year:
2019
Journal volume:
100
Journal issue:
2
Pages contribution:
127-138
Language:
eng
Fulltext / DOI:
doi:10.1159/000494252
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30423561
Print-ISSN:
0012-2823
TUM Institution:
II. Medizinische Klinik und Poliklinik (Gastroenterologie); Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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