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Title:

Single-Cell Resolution of T Cell Immune Responses.

Document type:
Journal Article
Author(s):
Buchholz, Veit R; Flossdorf, Michael
Abstract:
Single antigen-specific B or T lymphocytes are the smallest functional units, into which an adaptive immune response can be dissected. Today, novel high-throughput technologies are providing researches with increasingly complex information on the diverse phenotypic signatures of individual lymphocytes. With a focus on T cells, we summarize here, how computational approaches are becoming increasingly important to identify the relevant developmental boundaries and connections between these high-di...     »
Journal title abbreviation:
Adv Immunol
Year:
2018
Journal volume:
137
Pages contribution:
1-41
Language:
eng
Fulltext / DOI:
doi:10.1016/bs.ai.2017.12.001
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29455845
Print-ISSN:
0065-2776
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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