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Dokumenttyp:
Journal Article
Autor(en):
Mattii, M; Lovászi, M; Garzorz, N; Atenhan, A; Quaranta, M; Lauffer, F; Konstantinow, A; Küpper, M; Zouboulis, C C; Kemeny, L; Eyerich, K; Schmidt-Weber, C B; Tör?csik, D; Eyerich, S
Titel:
Sebocytes contribute to skin inflammation by promoting the differentiation of T helper 17 cells.
Abstract:
The main function of sebocytes is considered to be the production of lipids to moisturize the skin. However, it recently became apparent that sebocytes release chemokines and cytokines and respond to proinflammatory stimuli as well as the presence of bacteria.To analyse the functional communication between human sebocytes and T cells.Immunofluorescence stainings for CD4 and interleukin (IL)-17 were performed on acne sections and healthy skin. Migration assays and T-cell-stimulation cultures were...     »
Zeitschriftentitel:
Br J Dermatol
Jahr:
2018
Band / Volume:
178
Heft / Issue:
3
Seitenangaben Beitrag:
722-730
Sprache:
eng
Volltext / DOI:
doi:10.1111/bjd.15879
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28799643
Print-ISSN:
0007-0963
TUM Einrichtung:
Klinik und Poliklinik für Dermatologie und Allergologie; Molekulare Allergologie (Prof. Schmidt-Weber); Professur für Experimentelle Dermato-Immunologie (Prof. Eyerich)
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