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Titel:

Characterization of the honeybee venom proteins C1q-like protein and PVF1 and their allergenic potential.

Dokumenttyp:
Journal Article
Autor(en):
Russkamp, Dennis; Van Vaerenbergh, Matthias; Etzold, Stefanie; Eberlein, Bernadette; Darsow, Ulf; Schiener, Maximilian; De Smet, Lina; Absmaier, Magdalena; Biedermann, Tilo; Spillner, Edzard; Ollert, Markus; Jakob, Thilo; Schmidt-Weber, Carsten B; de Graaf, Dirk C; Blank, Simon
Abstract:
Honeybee (Apis mellifera) venom (HBV) represents an ideal model to study the role of particular venom components in allergic reactions in sensitized individuals as well as in the eusociality of Hymenoptera species. The aim of this study was to further characterize the HBV components C1q-like protein (C1q) and PDGF/VEGF-like factor 1 (PVF1). C1q and PVF1 were produced as recombinant proteins in insect cells. Their allergenic properties were examined by determining the level of specific IgE antibo...     »
Zeitschriftentitel:
Toxicon
Jahr:
2018
Band / Volume:
150
Seitenangaben Beitrag:
198-206
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.toxicon.2018.05.017
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29842867
Print-ISSN:
0041-0101
TUM Einrichtung:
Klinik und Poliklinik für Dermatologie und Allergologie; Molekulare Allergologie (Prof. Schmidt-Weber)
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