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Original title:
Eigenschaften mechanosensitiver Neurone des myenterischen und submukösen Plexus nach Deformation
Translated title:
Properties of mechanosensitive neurons in the myenteric and submucous plexus after deformation
Author:
Kreutz, Florian
Year:
2019
Document type:
Dissertation
Faculty/School:
Fakultät Wissenschaftszentrum Weihenstephan
Advisor:
Schemann, Michael (Prof. Dr.)
Referee:
Schemann, Michael (Prof. Dr.); Luksch, Harald (Prof. Dr.)
Language:
de
Subject group:
BIO Biowissenschaften
Keywords:
enterisches Nervensystem, Deformation, Mechanosensitivität, Kompression, Dehnung
Translated keywords:
enteric nervous system, deformation, mechanosensitivity, compression, stretch
TUM classification:
BIO 950d
Abstract:
Der Verdauungstrakt ist fortwährend mechanischen Spannungen ausgesetzt. Die Studie identifizierte mechanosensitive enterische Neurone (MEN) im submukösen Plexus, die kompressions- und/oder dehnungssensitiv sind. Kompressionssensitive MEN scheinen schnell zu adaptieren (rapidly adapting MEN, RAMEN) wohingegen dehnungssensitive MEN langsam adaptieren (slowly adapting MEN, SAMEN). Mechanisch gesteuerte Kationkanäle spielen möglicherweise eine wichtige Rolle bei der neuronalen Mechanotransduktion im...     »
Translated abstract:
The gastrointestinal tract is constantly under mechanical stress. This study identified mechanosensitive enteric neurons (MEN) in the submucous plexus, which are compression- and/or stretch-sensitive. Compression-sensitive MEN adapt rapidly (rapidly adapting MEN, RAMEN) whereas stretch-sensitive MEN adapt slowly (slowly adapting MEN, SAMEN). It also reveals, that mechanically gated cation channels, may play an important role in neuronal mechanotransduction in the enteric nervous system.
WWW:
https://mediatum.ub.tum.de/?id=1456211
Date of submission:
24.10.2018
Oral examination:
02.04.2019
File size:
2425698 bytes
Pages:
120
Urn (citeable URL):
https://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:91-diss-20190402-1456211-1-2
Last change:
23.04.2019
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