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Title:

Impact of body mass on P2Y12-inhibitor de-escalation in acute coronary syndromes-a substudy of the TROPICAL-ACS trial.

Document type:
Randomized Controlled Trial; Journal Article
Author(s):
Komócsi, András; Merkely, Béla; Hadamitzky, Martin; Massberg, Steffen; Rizas, Konstantinos D; Hein-Rothweiler, Ralph; Gross, Lisa; Trenk, Dietmar; Sibbing, Dirk; Aradi, Dániel
Abstract:
AIMS: Clinical guidelines recommend de-escalation antiplatelet strategies to reduce bleeding risk in acute coronary syndrome (ACS) patients, albeit with a weak recommendation. This substudy of the TROPICAL-ACS trial aimed to determine the impact of body mass on the efficacy of a platelet function testing-guided de-escalation regimen in ACS patients after percutaneous coronary intervention. METHODS AND RESULTS: Patients were randomized to prasugrel (control group) or a platelet function testing-g...     »
Journal title abbreviation:
Eur Heart J Cardiovasc Pharmacother
Year:
2023
Journal volume:
9
Journal issue:
7
Pages contribution:
608-616
Fulltext / DOI:
doi:10.1093/ehjcvp/pvad027
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37015874
Print-ISSN:
2055-6837
TUM Institution:
606; Institut für Radiologie und Nuklearmedizin
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