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Titel:

Dietary and supplemental intake of vitamins C and E is associated with altered DNA methylation in an epigenome-wide association study meta-analysis.

Dokumenttyp:
Meta-Analysis; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Intramural
Autor(en):
Keshawarz, Amena; Joehanes, Roby; Ma, Jiantao; Lee, Gha Young; Costeira, Ricardo; Tsai, Pei-Chien; Masachs, Olatz M; Bell, Jordana T; Wilson, Rory; Thorand, Barbara; Winkelmann, Juliane; Peters, Annette; Linseisen, Jakob; Waldenberger, Melanie; Lehtimäki, Terho; Mishra, Pashupati P; Kähönen, Mika; Raitakari, Olli; Helminen, Mika; Wang, Carol A; Melton, Phillip E; Huang, Rae-Chi; Pennell, Craig E; O'Sullivan, Therese A; Ochoa-Rosales, Carolina; Voortman, Trudy; van Meurs, Joyce B J; Young, Kristi...     »
Abstract:
BACKGROUND: Dietary intake of antioxidants such as vitamins C and E protect against oxidative stress, and may also be associated with altered DNA methylation patterns. METHODS: We meta-analysed epigenome-wide association study (EWAS) results from 11,866 participants across eight population-based cohorts to evaluate the association between self-reported dietary and supplemental intake of vitamins C and E with DNA methylation. EWAS were adjusted for age, sex, BMI, caloric intake, blood cell type p...     »
Zeitschriftentitel:
Epigenetics
Jahr:
2023
Band / Volume:
18
Heft / Issue:
1
Volltext / DOI:
doi:10.1080/15592294.2023.2211361
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/37233989
Print-ISSN:
1559-2294
TUM Einrichtung:
656; Institut für Humangenetik (Prof. Winkelmann)
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