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Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Ingen-Housz-Oro, S; Schmidt, V; Ameri, M M; Abe, R; Brassard, A; Mostaghimi, A; Paller, A S; Romano, A; Didona, B; Kaffenberger, B H; Ben Said, B; Thong, B Y H; Ramsay, B; Brezinova, E; Milpied, B; Mortz, C G; Chu, C Y; Sotozono, C; Gueudry, J; Fortune, D G; Dridi, S M; Tartar, D; Do-Pham, G; Gabison, E; Phillips, E J; Lewis, F; Salavastru, C; Horvath, B; Dart, J; Setterfield, J; Newman, J; Schulz, J T; Delcampe, A; Brockow, K; Seminario-Vidal, L; Jörg, L; Watson, M P; Gonçalo, M; Lucas, M; Torr...     »
Titel:
Post-acute phase and sequelae management of epidermal necrolysis: an international, multidisciplinary DELPHI-based consensus.
Abstract:
BACKGROUND: Long-term sequelae are frequent and often disabling after epidermal necrolysis (Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)). However, consensus on the modalities of management of these sequelae is lacking. OBJECTIVES: We conducted an international multicentric DELPHI exercise to establish a multidisciplinary expert consensus to standardize recommendations regarding management of SJS/TEN sequelae. METHODS: Participants were sent a survey via the online tool "Survey Monkey" consisting of 54 statements organized into 8 topics: general recommendations, professionals involved, skin, oral mucosa and teeth, eyes, genital area, mental health, and allergy workup. Participants evaluated the level of appropriateness of each statement on a scale of 1 (extremely inappropriate) to 9 (extremely appropriate). Results were analyzed according to the RAND/UCLA Appropriateness Method. RESULTS: Fifty-two healthcare professionals participated. After the first round, a consensus was obtained for 100% of 54 initially proposed statements (disagreement index < 1). Among them, 50 statements were agreed upon as 'appropriate'; four statements were considered 'uncertain', and ultimately finally discarded. CONCLUSIONS: Our DELPHI-based expert consensus should help guide physicians in conducting a prolonged multidisciplinary follow-up of sequelae in SJS-TEN.
Zeitschriftentitel:
Orphanet J Rare Dis
Jahr:
2023
Band / Volume:
18
Heft / Issue:
1
Volltext / DOI:
doi:10.1186/s13023-023-02631-7
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/36814255
Print-ISSN:
1750-1172
TUM Einrichtung:
600; Klinik und Poliklinik für Dermatologie und Allergologie (Prof. Biedermann)
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