User: Guest  Login
Title:

Yap/Taz activity is associated with increased expression of phosphoglycerate dehydrogenase that supports myoblast proliferation

Document type:
Zeitschriftenaufsatz
Author(s):
Meinhold, Marius; Verbrugge, Sander; Shi, Andi; Schönfelder, Martin; Becker, Lore; Jaspers, Richard T.; Zammit, Peter S.; Wackerhage, Henning
Abstract:
In skeletal muscle, the Hippo effector Yap promotes satellite cell, myoblast, and rhabdomyoblast proliferation but prevents myogenic differentiation into multinucleated muscle fibres. We previously noted that Yap drives expression of the first enzyme of the serine biosynthesis pathway, phosphoglycerate dehydrogenase (Phgdh). Here, we examined the regulation and function of Phgdh in satellite cells and myoblasts and found that Phgdh protein increased during satellite cell activation. Analysis of...     »
Dewey Decimal Classification:
570 Biowissenschaften, Biologie
Journal title:
Cell and Tissue Research
Year:
2024
Year / month:
2024-01
Quarter:
1. Quartal
Month:
Jan
Covered by:
Web of Science
Reviewed:
ja
Language:
en
Fulltext / DOI:
doi:10.1007/s00441-023-03851-w
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/38183459
WWW:
https://link.springer.com/article/10.1007/s00441-023-03851-w
Publisher:
Springer Science and Business Media LLC
E-ISSN:
0302-766X1432-0878
Impact Factor:
3,6
Scimago Quartil:
Q1
Notes:
SCImago Journal &  Country Rank
Status:
Erstveröffentlichung
Date of publication:
06.01.2024
Semester:
WS 23-24
TUM Institution:
Sportbiologie
Format:
Bild/Text
 BibTeX