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Title:

Neurotoxin-Derived Optical Probes for Biological and Medical Imaging.

Document type:
Review; Journal Article; Review; Research Support, Non-U.S. Gov't
Author(s):
Ergen, Pinar Helin; Shorter, Susan; Ntziachristos, Vasilis; Ovsepian, Saak Victor
Abstract:
The superb specificity and potency of biological toxins targeting various ion channels and receptors are of major interest for the delivery of therapeutics to distinct cell types and subcellular compartments. Fused with reporter proteins or labelled with fluorophores and nanocomposites, animal toxins and their detoxified variants also offer expanding opportunities for visualisation of a range of molecular processes and functions in preclinical models, as well as clinical studies. This article pr...     »
Journal title:
Molecular Imaging and Biology
Journal title abbreviation:
Mol Imaging Biol
Year:
2023
Journal volume:
25
Journal issue:
5
Pages contribution:
799-814
Fulltext / DOI:
doi:10.1007/s11307-023-01838-1
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37468801
WWW:
https://link.springer.com/article/10.1007/s11307-023-01838-1
Print-ISSN:
1536-1632
TUM Institution:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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