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Title:

177Lu-Prostate-Specific Membrane Antigen Therapy in Patients with Metastatic Castration-Resistant Prostate Cancer and Prior 223Ra (RALU Study).

Document type:
Multicenter Study; Journal Article
Author(s):
Rahbar, Kambiz; Essler, Markus; Eiber, Matthias; la Fougère, Christian; Prasad, Vikas; Fendler, Wolfgang P; Rassek, Philipp; Hasa, Ergela; Dittmann, Helmut; Bundschuh, Ralph A; Pabst, Kim M; Kurtinecz, Milena; Schmall, Anja; Verholen, Frank; Sartor, Oliver
Abstract:
223Ra-dichloride (223Ra) and 177Lu-prostate-specific membrane antigen (PSMA) are approved treatments for metastatic castration-resistant prostate cancer (mCRPC). The safety and effectiveness of sequential use of 223Ra and 177Lu-PSMA in patients with mCRPC are not well described. This study aimed to evaluate 177Lu-PSMA safety and efficacy in patients with mCRPC previously treated with 223Ra. Methods: The radium→lutetium (RALU) study was a multicenter, retrospective, medical chart review. Particip...     »
Journal title abbreviation:
J Nucl Med
Year:
2023
Journal volume:
64
Journal issue:
12
Pages contribution:
1925-1931
Fulltext / DOI:
doi:10.2967/jnumed.123.266125
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37827838
Print-ISSN:
0161-5505
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin (Prof. Weber)
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