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Title:

T1 and FLAIR signal intensities are related to tau pathology in dominantly inherited Alzheimer disease.

Document type:
Observational Study; Journal Article
Author(s):
Rahmani, Farzaneh; Brier, Matthew R; Gordon, Brian A; McKay, Nicole; Flores, Shaney; Keefe, Sarah; Hornbeck, Russ; Ances, Beau; Joseph-Mathurin, Nelly; Xiong, Chengjie; Wang, Guoqiao; Raji, Cyrus A; Libre-Guerra, Jorge J; Perrin, Richard J; McDade, Eric; Daniels, Alisha; Karch, Celeste; Day, Gregory S; Brickman, Adam M; Fulham, Michael; Jack, Clifford R; la La Fougère, Christian; Reischl, Gerald; Schofield, Peter R; Oh, Hwamee; Levin, Johannes; Vöglein, Jonathan; Cash, David M; Yakushev, Igor; I...     »
Abstract:
Carriers of mutations responsible for dominantly inherited Alzheimer disease provide a unique opportunity to study potential imaging biomarkers. Biomarkers based on routinely acquired clinical MR images, could supplement the extant invasive or logistically challenging) biomarker studies. We used 1104 longitudinal MR, 324 amyloid beta, and 87 tau positron emission tomography imaging sessions from 525 participants enrolled in the Dominantly Inherited Alzheimer Network Observational Study to extrac...     »
Journal title abbreviation:
Hum Brain Mapp
Year:
2023
Journal volume:
44
Journal issue:
18
Pages contribution:
6375-6387
Fulltext / DOI:
doi:10.1002/hbm.26514
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37867465
Print-ISSN:
1065-9471
TUM Institution:
170; 617; Klinik und Poliklinik für Nuklearmedizin (Prof. Weber)
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