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Role of Cell-Based Therapies in T2D.
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2023
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Cochrane, Veronica A;Hebrok, Matthias
Stem cell-derived islet therapy: is this the end of the beginning?
Nat Rev Endocrinol
2023
19
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Chendke, Gauree S;Kharbikar, Bhushan N;Ashe, Sudipta;Faleo, Gaetano;Sneddon, Julie B;Tang, Qizhi;Hebrok, Matthias;Desai, Tejal A
Replenishable prevascularized cell encapsulation devices increase graft survival and function in the subcutaneous space.
Bioeng Transl Med
2023
8
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Lutter, Dominik;Sachs, Stephan;Walter, Marc;Kerege, Anna;Perreault, Leigh;Kahn, Darcy E;Wolide, Amare D;Kleinert, Maximilian;Bergman, Bryan C;Hofmann, Susanna M
Skeletal muscle and intermuscular adipose tissue gene expression profiling identifies new biomarkers with prognostic significance for insulin resistance progression and intervention response.
Diabetologia
2023
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Gruber, Tim;Lechner, Franziska;Murat, Cahuê;Contreras, Raian E;Sanchez-Quant, Eva;Miok, Viktorian;Makris, Konstantinos;Le Thuc, Ophélia;González-García, Ismael;García-Clave, Elena;Althammer, Ferdinand;Krabichler, Quirin;DeCamp, Lisa M;Jones, Russell G;Lutter, Dominik;Williams, Rhiannan H;Pfluger, Paul T;Müller, Timo D;Woods, Stephen C;Pospisilik, John Andrew;Martinez-Jimenez, Celia P;Tschöp, Matthias H;Grinevich, Valery;García-Cáceres, Cristina
High-calorie diets uncouple hypothalamic oxytocin neurons from a gut-to-brain satiation pathway via κ-opioid signaling.
Cell Rep
2023
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Becker, Maike;Joseph, Sini S;Garcia-Carrizo, Francisco;Tom, Robby Z;Opaleva, Daria;Serr, Isabelle;Tschöp, Matthias H;Schulz, Tim J;Hofmann, Susanna M;Daniel, Carolin
Regulatory T cells require IL6 receptor alpha signaling to control skeletal muscle function and regeneration.
Cell Metab
2023
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Campbell, Jonathan E;Müller, Timo D;Finan, Brian;DiMarchi, Richard D;Tschöp, Matthias H;D'Alessio, David A
GIPR/GLP-1R dual agonist therapies for diabetes and weight loss-chemistry, physiology, and clinical applications.
Cell Metab
2023
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Liskiewicz, Arkadiusz;Khalil, Ahmed;Liskiewicz, Daniela;Novikoff, Aaron;Grandl, Gerald;Maity-Kumar, Gandhari;Gutgesell, Robert M;Bakhti, Mostafa;Bastidas-Ponce, Aimée;Czarnecki, Oliver;Makris, Konstantinos;Lickert, Heiko;Feuchtinger, Annette;Tost, Monica;Coupland, Callum;Ständer, Lisa;Akindehin, Seun;Prakash, Sneha;Abrar, Faiyaz;Castelino, Russell L;He, Yantao;Knerr, Patrick J;Yang, Bin;Hogendorf, Wouter F J;Zhang, Shiqi;Hofmann, Susanna M;Finan, Brian;DiMarchi, Richard D;Tschöp, Matthias H;Douros, Jonathan D;Müller, Timo D
Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice.
Nat Metab
2023
5
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Tschöp, Matthias H;Friedman, Jeffrey M
Seeking satiety: From signals to solutions.
Sci Transl Med
2023
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Alkhoury, Chantal;Henneman, Nathaniel F;Petrenko, Volodymyr;Shibayama, Yui;Segaloni, Arianna;Gadault, Alexis;Nemazanyy, Ivan;Le Guillou, Edouard;Wolide, Amare Desalegn;Antoniadou, Konstantina;Tong, Xin;Tamaru, Teruya;Ozawa, Takeaki;Girard, Muriel;Hnia, Karim;Lutter, Dominik;Dibner, Charna;Panasyuk, Ganna
Class 3 PI3K coactivates the circadian clock to promote rhythmic de novo purine synthesis.
Nat Cell Biol
2023
25
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975-988