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Title:

Multifunctional croconaine nanoparticles for efficient optoacoustic imaging of deep tumors and photothermal therapy

Document type:
Zeitschriftenaufsatz
Author(s):
Liu, Nian; O'Connor, Patrick; Gujrati, Vipul; Anzenhofer, Pia; Klemm, Uwe; Kleigrewe, Karin; Sattler, Michael; Plettenburg, Oliver; Ntziachristos, Vasilis
Abstract:
The proper design of near-infrared light-absorbing agents enables efficient optoacoustic imaging-guided phototherapy. In particular, several croconaine-based organic agents with excellent optical properties have been recently reported for this purpose. However, most of them absorb light below 800 nm, limiting deep-tissue imaging applications. To this end, we utilized a recently described novel croconaine derivative (CR880) to develop CR880-based nanoparticles (CR880-NPs) for effective in vivo de...     »
Journal title:
Nanophotonics
Journal title abbreviation:
Nanophotonics
Year:
2022
Journal volume:
11
Journal issue:
21
Pages contribution:
4637-4647
Fulltext / DOI:
doi:10.1515/nanoph-2022-0469
WWW:
https://www.degruyter.com/document/doi/10.1515/nanoph-2022-0469/html
Print-ISSN:
2192-8606
TUM Institution:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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