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Titel:

The neglected twin: Nummular eczema is a variant of atopic dermatitis with codominant TH2/TH17 immune response.

Dokumenttyp:
Article; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Böhner, Alexander; Jargosch, Manja; Müller, Nikola S; Garzorz-Stark, Natalie; Pilz, Caroline; Lauffer, Felix; Wang, Rosi; Roenneberg, Sophie; Zink, Alexander; Thomas, Jenny; Theis, Fabian J; Biedermann, Tilo; Eyerich, Stefanie; Eyerich, Kilian
Abstract:
BACKGROUND: Nummular eczema (NE) is a common chronic inflammatory skin disease characterized by multiple, pruritic, discoid-shaped lesions. Since the underlying immune mechanisms are not fully understood, it is unclear whether NE should be regarded as variant of atopic dermatitis (AD) or a distinct disease. OBJECTIVE: We compared the clinical, histopathologic, and molecular signatures of NE with that of type 2 and type 3 skin diseases. METHODS: We performed bulk RNA sequencing as well as histolo...     »
Zeitschriftentitel:
J Allergy Clin Immunol
Jahr:
2023
Band / Volume:
152
Heft / Issue:
2
Seitenangaben Beitrag:
408-419
Volltext / DOI:
doi:10.1016/j.jaci.2023.04.009
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/37119871
Print-ISSN:
0091-6749
TUM Einrichtung:
Klinik und Poliklinik für Dermatologie und Allergologie (Prof. Biedermann)
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