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Title:

Microglia states and nomenclature: A field at its crossroads.

Document type:
Journal Article; Review; Research Support, Non-U.S. Gov't
Author(s):
Paolicelli, Rosa C; Sierra, Amanda; Stevens, Beth; Tremblay, Marie-Eve; Aguzzi, Adriano; Ajami, Bahareh; Amit, Ido; Audinat, Etienne; Bechmann, Ingo; Bennett, Mariko; Bennett, Frederick; Bessis, Alain; Biber, Knut; Bilbo, Staci; Blurton-Jones, Mathew; Boddeke, Erik; Brites, Dora; Brône, Bert; Brown, Guy C; Butovsky, Oleg; Carson, Monica J; Castellano, Bernardo; Colonna, Marco; Cowley, Sally A; Cunningham, Colm; Davalos, Dimitrios; De Jager, Philip L; de Strooper, Bart; Denes, Adam; Eggen, Bart J...     »
Abstract:
Microglial research has advanced considerably in recent decades yet has been constrained by a rolling series of dichotomies such as "resting versus activated" and "M1 versus M2." This dualistic classification of good or bad microglia is inconsistent with the wide repertoire of microglial states and functions in development, plasticity, aging, and diseases that were elucidated in recent years. New designations continuously arising in an attempt to describe the different microglial states, notably...     »
Journal title abbreviation:
Neuron
Year:
2022
Journal volume:
110
Journal issue:
21
Pages contribution:
3458-3483
Fulltext / DOI:
doi:10.1016/j.neuron.2022.10.020
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/36327895
Print-ISSN:
0896-6273
TUM Institution:
Klinik und Poliklinik für Psychiatrie und Psychotherapie; Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)
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